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FIGURE 6 Collectively, these studies demonstrate the significant therapeutic potential of cerium oxide-based nanomaterialssuch as CNP-miR146a, CS-TA@CeO 2 cryogel, and SBQCC/CNPs powderin addressing key pathological features of diabetic wounds

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The study is well-rounded, with robust in vitro demonstrations in E9 endothelial cells and in vivo studies in Zebrafish larvae and chick embryo models

(2021) COVID-19: our current knowledge of epidemiology, pathology, therapeutic approaches, and diagnostic methods

2013 Dec;5(2):20

Then they further optimized the design and synthesized two kinds of lactam-stapled peptides to study their properties on helicity, bioactivity, and cell uptake, in which the lactam-stapled peptide galactose-6-phosphate isomerase subunit (LacB)-4E-BP1 exhibits extremely high cellular uptake efficiency (84% 20%) that is sufficient to bind to the cell membrane, trigger endocytosis and subsequently lead to endosome escape [162]