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Transactions Of The American Clinical And Climatological Association 1992, 103: 157-63

Al-Rubeaan et al

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and the University of Pavias Department of Biology and Biotechnology, alongside CDC Dermo-Clinical Research Institute

These effects are partly mediated by suppression of nocturnal cortisol and restoration of the physiological melatonin-insulin rhythm, which is often blunted in PCOS due to circadian misalignment (200)