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Acetylcarnitine has been reported to function as a secretagogue of insulin, whereas the accumulation of stearoylcarnitine (C18-carnitine) in cells has been shown to impair insulin synthesis [71]

Elsnerova et al., 2016

As the mitochondria produce less energy, the energy they do create must be used for bare essential short-term survival processes

Halliwell et al., 2016)

The purpose of this review is to comprehensively summarize the multidimensional biological effects of the carnitine pool beyond its traditional role in fatty acid oxidation and to summarize the systemic effects mediated by carnitine/acylcarnitine to provide new perspectives for pharmacological research and treatment innovation and new strategies for the prevention and treatment of a variety of diseases

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