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However, existing in vitro BBB models cannot mimic these dynamic pathological changes and spatial heterogeneity, leading to fundamental limitations in predicting drug permeability and the therapeutic window

Gastrointestinal symptoms such as loss of appetite, constipation, or diarrhoea may also occur, though these are non-specific and can have many causes

Souhaitons que cette explication rduise en partie la confusion, plutt que den crer davantage

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