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For instance, lnRNAs RP5-833A20.1 and E330013P60 are upregulated in foam cells and macrophages under hyperglycemic conditions, which increases the expression of inflammatory cytokines, including IL-1, IL-6, and TNF, and promotes pro-inflammatory macrophage phenotypes through mechanisms involving miR-382-5p induction and NFIA suppression [141]

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Lee, University of North Carolina at Chapel Hill, United States