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2021 Oct 1;115:8-22

Pulmonary medication adherence and health-care use in cystic fibrosis

The presence of vitamin C and vitamin E helps in maintaining youthful skin, prevents the breakdown of elastin as well as collagen due to increased oxidative stress

Mechanistically, this strategy led to the downregulation of NF-B, activation of FADD, and increased expression of APAF1 and E-cadherin, while suppressing tumour-promoting factors such as Survivin, MDR1, STAT3, Akt, PI3K, and vimentin [253]

The outcomes were 90-day rates of overall survival (with LT as a competing risk), transplant-free survival, and rates of LT with associated time to transplant, as well as resource utilization during hospitalization

NAC acts as a powerful antioxidant that helps neutralize oxidative stress before it damages skin cells