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This was due to reports that FIN could increase the expression of BCL-2 and decrease the expressions of CC3 and BAX [76, 77]

It converts GSH to oxidized glutathione (GSSG) and reduces lipid peroxidation, thereby reducing lipid peroxide formation and oxidative stress damage and ultimately inhibiting Ferroptosis (Figure 2)

Nature 500, 422426

10.1021/acs.jafc.2c06311 60 LeiP.TianS.TengC.HuangL.LiuX.WangJ.et al (2019)

Thus, traditional Chinese medicine, Tibetan medicine, and other ethnic medicines frequently consist of compound formulations containing diverse flavonoids