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The relative difference in gene expression level was calculated using the delta-delta-cycle threshold method

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Future studies are likely to explore additional combination therapies, particularly those involving drugs with distinct mechanisms of action, such as pairing iron chelators with antioxidants or mitochondrial protectants (64)

Virtually all of the conjugated products are pharmacologically inactive, with some important exceptions (e.g., morphine glucuronide)

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The result is increased superoxide production, which in turn inhibits prolyl hydroxylase, seemingly through oxidation of cysteine residues [117]