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Therefore, the findings should not be presented as clear evidence that alkaline water improves bone density, but rather as preliminary evidence requiring longer follow-up and further controlled investigation (69)

R.LiS.HouM.et al (2023)

In HCC, a dynamic interplay exists between tumor cell metabolic reprogramming and the enrichment and functional enhancement of Tregs [125,126]

Immediate-release preparations produce peak serum concentrations within hours, but sustained-release lithium may not peak for 6 to 12 hours

Metabolic and Detoxification Support Glutathione plays a crucial role in liver function, where detoxification occurs

Table 5 systematically compares key characteristics of MEVs with other widely studied extracellular vesiclesmesenchymal stem cell-derived EVs and cancer-derived EVshighlighting critical challenges in scalability, stability, targeting capability, and ethical considerations for clinical translation