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LPC and cuprizone demyelination induce transcriptionally similar DAM states that persist through remyelination In addition to OL lineage alterations, demyelination induced dramatic changes in microglia abundance and state (Fig

Until now, numerous bioactive molecules with recognized neuroprotective mechanismssuch as polyphenols, terpenes, and alkaloidshave been extracted from plants and identified for their therapeutic potential in PD

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INH is subject to metabolism through the actions of N-acetyltransferase and CYP2E1

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