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Sugar alcohols such as xylitol and erythritol occupy a middle ground between sugar and synthetic sweeteners , providing fewer calories whilst maintaining some metabolic activity

doi:10.1016/j.jnutbio.2004.04.009 Ho A, Michelson D, Aaen G, Ashwal S (2010) Cerebral folate deficiency presenting as adolescent catatonic schizophrenia: a case report

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Because of their potency, they must be used with care, especially when layering, to avoid irritation or neutralizing their effects

Additionally, there is the potential to modify the underlying disease with IL-23 inhibitors

Enzymatic synthesis of SCV-07 can be a promising alternative to meet the future demand of this prospective drug