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In this study, regarding the healthy volunteers, the authors reported in inflammatory response syndrome patients a significantly lower count of obligate anaerobic bacteria ( Bacteroidaceae , Bifidobacterium , and Enterobacteriaceae ) and a significantly higher count of facultative anaerobic microorganisms ( Enterococcus , Staphylococcus , Pseudomonas , and Candida )

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Acknowledgements The authors thank Prof Marie-Paule Strub and August Bck for providing the E

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A variant associated with lower GLP-1 receptor expression might suggest stronger benefit from combined GLP-1 and AMPK-targeted therapies like berberine, but this should be interpreted with a qualified healthcare provider who knows your full clinical picture

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