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Mutations outside of this CMT hotspot would not be expected to impact this interaction network and have not been explored biochemically or structurally

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Moreover, the majority of hepatocytes preserved the expression of the drug metabolizing enzyme CYP3A4 over 7 days, as previously shown 32

Selection of Six Eryptosis Inducers of Interest Six eryptosis inducers were selected based on their clinical use (or potential use), their known molecular targets and/or their demonstrated impact on Plasmodium development (summarized in Table 1 )