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In summary, we have been able to confirm that levels of glutathione, the most abundant antioxidant, are significantly lower in WB and erythrocytes in older, senior cats compared with younger adult cats

Puerarin attenuates diabetic kidney injury through the suppression of nox4 expression in podocytes

The inflammation-cancer axis is thus a well-established pathway in gastric carcinogenesis, making anti-inflammatory interventions a rational strategy for prevention [14, 15]

2.1.5 CircRNAs that inhibit ferroptosis via other pathways Some circRNAs have also been reported to inhibit ferroptosis via signal transducer and activator of transcription 3 (STAT3), platelet derived growth factor receptor alpha (PDGFRA), integrin subunit beta 8 (ITGB8), and other pathways and play important regulatory roles in the progression of various cancers, such as breast cancer, glioma, lung cancer, HCC, colorectal cancer, ALL, and esophageal cancer (Zhang et al., 2020a