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This is the most important caveat for beginners, and the one most vendor pages omit

Matrix Metalloproteinase-9 (MMP-9) What it measures: Tissue breakdown and remodeling

Copper in excess is genuinely toxic, and in a zebrafish model free copper caused heart toxicity (Hsiao et al., 2020) though in that same study the GHK peptide chelated copper and reduced the harm, so GHK-Cu is not equivalent to free copper

The peptide altered 127 genes in these cells, upregulating repair genes while downregulating inflammatory pathways responsible for tissue destruction

If you are dealing with oily skin, large pores, and frequent breakouts, this is the Niacinamide serum that actually sorts it all out

This is a secondary effect of overall matrix improvement, not a direct pore-targeting action