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Salivary gland injury after radiation directly triggers hyposalivation

After removing the final wash, the beads were incubated twice at room temperature in 80 l of the digestion buffer (2 M urea, 50 mM Tris-HCl, 1 mM DTT and 0.4 g of trypsin) while shaking at 1,000 rpm

[18] O'Donnell JP, Bhavnani SM

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Some researchers also track NAD+ metabolite levels via urinary nicotinamide excretion to confirm functional NNMT inhibition, though this is not standard practice

2012) and that our ability to explore this experimentally is restricted by the limited metabolic capability and poor relevance to humans in vivo of many currently available in vitro toxicological models (Park et al