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For example, boosting NAD + through NR administration could confer anti-inflammatory effects on tissue macrophages, in which NR supplementation attenuated the type I IFN signaling pathway, an important myeloid regulatory program, through the increased inosine level and the subsequent suppression of autophagy [97]

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Funding This study was supported by the Guangdong Medical Science and Technology Research Foundation (A2022479), the Guangdong Basic and Applied Basic Research Foundation (2023A1515011699), the University-Hospital Joint Fund Project of Guangzhou University of Chinese Medicine (GZYZS2024U08), and the Scientific Research Project of Guangdong Provincial Administration of Traditional Chinese Medicine(20251432)

But if you dont get enough of any one of these vitamins, you may experience fatigue, weakness, or have difficulty concentrating

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Tohoku J Exp Med (2010) 221(4):28798