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Advances in AAV technology for delivering genetically encoded cargo to the nonhuman primate nervous system

Continual synthesis of endogenous glutathione is essential for normal growth and development (20), but the importance of maintaining the correct ratio of reduced:oxidised glutathione in Bd was unknown

Last, to determine the impact of AKT-dependent regulation of glycolysis on NADPH production we used Fluorescence Lifetime Imaging Microscopy (FLIM) technology to compare NADPH/NADH ratio in AKT-E17K and AKT-WT TrC1 in untreated controls and upon irradiation with 5 Gy with and without additional treatment with the AKT-inhibitor MK2206 ( Figure S3E, F )

Comparative profile of heme acquisition genes in disease-causing and colonizing nontypeable Haemophilus influenzae and Haemophilus haemolyticus

K d values is the average of at least three separate experiments and the error was calculated as the standard deviation between the runs