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Thus, modulating ferroptosis can also impact apoptosis (99)

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Critically, acute AMPK activation during ATP depletion exacerbates glycolytic overdrive and FAO, while chronic mTORC1 signaling in surviving neurons drives maladaptive lipid synthesis that fuels ferroptosis [111]

J Clin Invest 34:622628 McKhann GM, Tower DB (1961) Ammonia toxicity and cerebral oxidative metabolism

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