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both are under positive selection in cetaceans (Tian et al., 2016)

is supported by the Intramural Research Program of the National Heart, Lung, and Blood Institute at the National Institutes of Health (NIH)

Studies in growth hormone-deficient mice show that while other growth hormone secretagogues increased body fat through growth hormone-independent mechanisms that included increased feeding, ipamorelin's effects on body composition are primarily mediated through its growth hormone-releasing properties