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The NAD+-driven increase in cellular energetics can amplify stimulant effects, producing jitteriness or insomnia if dosed too late in the day

S.BorgmeyerU.MangelsdorfD

2024;5:e531

The inhibitory effect of ketamine on prkcg in promoting apoptosis provides further grounds for more extensively examining the more general effects of ketamine in relation to prkcg, in order to further illuminate potential ketamine mechanisms of action

Additionally, the interindividual variability in gut microbiota composition significantly influences polyphenol biotransformation into bioactive metabolites, complicating the prediction of therapeutic outcomes and impeding the standardization of treatments (Cardona et al