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HCV particles enter cells via a multistep process involving numerous cell surface proteins, cellular processing of virus-associated lipoproteins, signal transduction events, clathrin-mediated internalization of the virus, and low-pH-induced membrane fusion

Furin-mediated priming of viral S protein at S1/S2 (P R RA R 685 ) [the underlined AAs refer to critical residues needed for the furin recognition] is a key determinant in the pathogenesis of COVID-19 55,73,329

This Review summarizes the biological mechanisms of cellular injury, perfusate modifications and mechanistic approaches for reinstating circulation, and offers perspectives on the future of organ and whole-body recovery

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