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In Nrf2 knockout rats, the constitutive activity of the choroidal glutathione-dependent detoxifying machinery is maintained, but the efficacy of dimethylfumarate to induce glutathione conjugation in the choroid plexuses is strongly reduced, indicating that dimethylfumarate acts mainly through the Nrf2 signaling pathway

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[27] Examples [edit] Human proteins that belong to this family include GGT1, GGT2, GGT6, GGTL3, GGTL4, GGTLA1 and GGTLA4

The transsulfuration pathway has a very limited tissue distribution

A herniated disc is one in which the discs inner cartilage, which is softer, can move through the crack to touch the surrounding nerves

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