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Studies have also identified several molecular targets involved in gemcitabine resistance that modulate ferroptosis sensitivity

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PMID: 412099

This approach revealed that the metabolic compensatory pathways that enable cells to overcome glutamine depletion are contingent on the capacity to synthesize glutamine via glutamine synthetase

UV radiation, especially UVA and UVB, triggers ROS production in melanocytes, leading to oxidative DNA damage that can initiate oncogenic mutations