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Diagnostic biomarkers in Alzheimers disease

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Recent studies in breast cancer have shown that linoleic acid induces ferroptosis through ACSL1-mediated incorporation into membrane lipids, promoting lipid peroxidation without directly inhibiting GPX4

Mito-Met 10 ), with enhanced mitochondrial targeting capacity, have been demonstrated to enhance metformin-mediated inhibition of mitochondrial respiration and radiosensitisation in prostate cancer ( in vitro and ex vivo models of oesophageal adenocarcinoma ( We also demonstrate metformin-mediated alterations to cell cycle distribution and progression following radiation in HCT116 and SW837 cells, with metformin demonstrated to reduce the proportion of G2/M phase cells and prevent radiation-induced G2/M blockade in these cells

Storch K-F, Lipan O, Leykin I, Viswanathan N, Davis FC, Wong WH, Weitz CJ (2002) Extensive and divergent circadian gene expression in liver and heart

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