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In contrast, M-CuP showed negligible binding to either target, with maximal responses below 5 response units (RU) across all tested concentrations, confirming the essential role of multivalent architecture in cooperative target engagement

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The post-synaptic currents, which were recorded in the presence of strychnine, picrotoxin and tetrodotoxin, represented spontaneous bursts likely mediated by AMPA receptors

Mobility issues: The excess skin restricts your movement or makes exercise uncomfortable

No genotoxicity, mutagenicity, or organ-specific toxicity was reported at the doses tested in the preclinical safety evaluation

Steinau S