does glutathione peroxidase have iron Impact of carbonylation on peroxidase-1 activity in human hyperglycemic endothelial cells The glutathione peroxidase Gpx4 prevents

The glutathione peroxidase Gpx4 prevents lipid peroxidation and ferroptosis to sustain Treg cell activation and suppression of antitumor immunity ScienceDirect Ferroptosis: a potential bridge linking gut microbiota and chronic kidney disease Cell Death Discovery Oxidative stress, eryptosis and anemia: a pivotal mechanistic nexus in systemic diseases Bissinger 2019 The FEBS Journal Wiley Online Library Ferroptosis regulation in lysosome Lysosomal iron and cathepsin B contribute to ferroptotic cell death. Lysosomal cyst(e)ine can be mobilized to maintain glutathione synthesis and glutathione peroxidase 4 activity, thereby limiting lipid peroxidation. Ferroptosis in Toxicology: Present and Future Sustained dysregulation of iron and glutathione homeostasis induces chronoferroptosis, a persistent ferroptotic adaptation in neuronal cells Cell Death Discovery

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