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Restoration of leptin responsiveness in diet-induced obese mice using an optimized leptin analog in combination with exendin-4 or FGF21

The major source of mitochondrial free radicals is the half-reduced semiquinone of co-enzyme Q (Chance et al., 2 to form the superoxide radical O 2

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These authors also found that the rate of reduction of nitrate to nitrite was dependent on the abundance of nitrate-reducing bacteria in the oral cavity