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Ferroptocide (FPT) is an active small molecule natural product modifier capable of inducing ferroptosis by covalently modifying the active site of thioredoxin (TNX), thereby interfering with the cellular antioxidant system and altering lipid peroxidation and redox status

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In the context of CKD, iron deposition is accompanied by the increased expression of iron input proteins (ZRT/IRT-like proteins, ZIP14 and ZIP8) or the decrease in FPN1 expression, indicating that iron accumulation may be triggered by increased iron uptake or insufficient iron efflux (Fig

Oncology 48(4):277281 Qasqas SA, McPherson C, Frishman WH, Elkayam U (2004) Cardiovascular pharmacotherapeutic considerations during pregnancy and lactation

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Recent neuroimaging studies suggest that adherence to the MIND diet correlates with preserved gray matter volume and cortical thickness, although more longitudinal evidence is warranted (Staubo et al., 2017)