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CFTR has physiological functions as a chloride and bicarbonate channel and a role in regulating water movement

doi: 10.1016/j.ejca.2021.10.027

doi: 10.3389/fonc.2020.591342 Received 04 August 2020 Accepted 30 November 2020 Published 15 January 2021 Volume 10 - 2020 Edited by Rentian Feng, University of Pittsburgh, United States Reviewed by Yogesh Chawla, Mayo Clinic, United States

1, 451459.10.1016/j.actbio.2005.04.004 98 MontesanoR.KumarS.OrciL.PepperM

Gene expression studies using microarray analysis reported that GHK-Cu at low nanomolar concentrations influenced the expression of over 4,000 human genes in fibroblast models, including upregulation of collagen I, collagen III, and elastin synthesis, and modulation of matrix metalloproteinase activity (Pickart and Margolina, Symmetry 2018)