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e.g., glyoxal, methylglyoxal or carboxymethyl-lysine) are heterogenous group of toxic compounds synthesized in the body through both exogenous and endogenous pathways

Acetylated glutathione not only increases the stability and lipophilicity of Glutathione but also allows it to sneak past the cellular defenses and enter cells more efficiently (Cacciatore et al., 2010)

Activation of the CDC42 effector N-WASP by the Shigella flexneri IcsA protein promotes actin nucleation by Arp2/3 complex and bacterial actin-based motility

Factors such as cost savings, convenience, absorption issues, potential digestion, and comfort with self-administering injections can affect patients preferences

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Nonetheless, whether ferroptotic cell death is associated with the effects of GSH depletion on RPE is unknown