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"Chelation therapy for heart disease: Does it work?" (Press release)

Notably, the voltage-dependent anion channel (VDAC) in the mitochondrial outer membrane, also known as the mitochondrial pore, acts as a gatekeeper for the entry and exit of mitochondrial metabolites and is a convergence point for its binding to various ligands and proteins to mediate various cell survival and cell death signals [47]

Oxidative stress is associated with induction of neurosteroid biosynthesis in the human brain (284), and TSPO ligands ( N , N -dialkyl-2-phenylindol-3-ylglyoxylamides) that also show anxiolytic activity promote a reduction in oxidative stress and pro-inflammatory enzymes in glial cells via promotion of neurosteroid synthesis (133)

HouKShenJYanJZhaiCZhangJPanJAet alLoss of TRIM21 alleviates cardiotoxicity by suppressing ferroptosis induced by the chemotherapeutic agent doxorubicin

The expression of SNCA, one gene related to PD, is specific to neurons and blood cells

Ni, Y.-L