1833-A IDENTIFYING THE POPULATION AT RISK OF HCC IN NON-ACLD CHRONIC HEPATITIS C PATIENTS CURED BY DIRECT-ACTING AGENTS: A STRATEGIC APPROACH Yen-Chun Liu 1,2 , Ya-Ting Cheng 1,2 , Yi-Cheng Chen 1,2 , Rachel Wen-Juei Jeng 1,2 , Chun-Yen Lin 1,2 , Rong-Nan Chien 1,2 , Dar-In Tai 1,2 , I-Shyan Sheen 1,2 and Yi-Chung Hsieh 1,2 , (1)Chang Gung Memorial Hospital, Linkou Branch, Taiwan, (2)College of Medicine, Chang Gung University, Taiwan Background: HCC surveillance is recommended for chronic hepatitis C (CHC) patients with advanced fibrosis (F3) or cirrhosis (F4) after successful viral eradication, according to clinical guidelines
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Abbreviations AP-1: Activator protein-1 CAPE: Caffeic acid phenethyl ester EC: Endothelial cell EGCG: Epigallocatechin gallate FLASH Therapy: Flashed High-dose Rate Radiotherapy FOXO: Forkhead box GPx: Glutathione peroxidase GR: Glutathione reductase IL-8: Interleukin-8 IV: Intravenous NOX: NADPH oxidase NF- B: NF-kappa B Nrf2: Nuclear factor-E2-associated factor 2 PI3K-AKT-mTOR: Phosphoinositide 3-kinase\ Protein Kinase B\ Mammalian Target of Rapamycin ROS: Reactive oxygen species REV: Resveratrol SOD: Superoxide dismutase TNF- : Tumor necrosis factor-alpha DHC: Dihydrocurcumin THC: Tetrahydrocurcumin HHC: Hexahydrocurcumin OHC: Octahydrocurcumin References Bray, F., Jemal, A., Grey, N., Ferlay, J
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