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86 The oral anti-diabetic drug metformin can also reduce the stability of SLC7A11 by inhibiting UFMylation of SLC7A11, and its combination with sulfasalazine can synergistically induce ferroptosis in breast cancer cells

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Hypoxia stress induces tissue damage, immune defense, and oxygen transport change in gill of silver carp ( Hypophthalmichthys molitrix ): evaluation on hypoxia by using transcriptomics

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Cyclosporin A (CsA) binds to cyclophilin D in mitochondria, targets MPTP and inhibits its excessive opening, thereby attenuating apoptosis and mitochondrial damage, and it has shown promising efficacy in in vivo experiments (animal models) (Chen et al., 2021a)