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[9] In addition to classification according to their pharmacological activities, grouping according to molecule types (antibody-based drugs, Fc fusion proteins, anticoagulants, blood factors, bone morphogenetic proteins, engineered protein scaffolds, enzymes, growth factors, hormones, interferons, interleukins, and thrombolytics) and molecular mechanisms (binding non-covalently to target, e.g

CANE demonstrates the capacity to cause apoptosis, senescence, cell cycle arrest, and suppress autophagy in A549DR cells, indicating its potential as a therapeutic option for lung cancer therapy (149)

Berberine inhibits growth of liver cancer cells by suppressing glutamine uptake

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doi: 10.1186/s12967-019-1885-4 109 HunterC

Toll-like receptor 7 (TLR7)-driven accumulation of a novel CD11c + B-cell population is important for the development of autoimmunity