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Additionally, 1033 ferroptosis-related genes were identified from GeneCards, NCBI, and MSigDB databases ( Supplementary Table 1 ) as a crucial gene set for intersection analysis between RA-related genes and gut microbiota metabolic pathways

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The exercise-induced increase in LPO content was reverted by supplementation with MSM, pointing to an improvement in the oxidative status of the cells, according to the MSM-induced increase of GSH previously mentioned

As seen with the knee joint angle (as well as ankle joint angle, hip joint angle) assessment, the treated animal stop to exhibit spontaneous injured hind limb contracture, and in particular, maintains knee extension, ability to achieve an additional knee extension upon forced extension

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Routes of administration studied: Oral route: Thanks to its stability in acidic environments, BPC-157 can be administered orally