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M-CSF cultured M0 cells are similar to M2, and M1 cytokines push M0 cells toward a pro-inflammatory state

Similarly, exposure to methylglyoxal, a reactive dicarbonyl compound formed as a metabolic byproduct of glycolysis, has been shown to inhibit glycolysis, leading to a reduction in ATP and GSH concentrations

Diez V, Traikov S, Schmeisser K et al (2021) Glycolate combats massive oxidative stress by restoring redox potential in caenorhabditis elegans

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Protective roles of ascorbic acid in oxidative stress induced by depletion of superoxide dismutase in vertebrate cells

1 So, its crucial to avoid sharing towels, lip balms or utensils during an outbreak