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10.5603/PJNNS.a2023.0010 [DOI] [PubMed] 22.Gorenshtein A, Leibovitch L, Liba T, Stern S, Stern Y

Anesthetic agents such as propofol and dexmedetomidine also protect against I/R injury by inhibiting mitochondrial apoptosis and inflammation mediated by this pathway[46, 47]

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Thun MJ, Calle EE, Namboodiri MM, Flanders WD, Coates RJ, Byers T, Boffetta P, Garfinkel L, Heath CW: Risk factors for fatal colon cancer in a large prospective study

However, germline mutations in C/EBP in acute myeloid leukemia (AML) truncate the N-terminus, leading to the loss of function of P42, resulting in an increase in the relative expression of P30 and an imbalance in the ratio between P42 and P30 [47]

They are being developed as drugs for the treatment of excessive inflammatory responses to infections with gram-negative bacteria