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The main source of conflicts is about stakeholder interests especially for material and procedural interests

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The upregulation of HDAC1 expression leads to the silencing of microglia/macrophage WAP domain protein (AMWAP), which further results in epithelial cell apoptosis, kidney damage, and inflammatory responses

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Furthermore, the compensatory hyperinsulinemia resulting from adipose dysfunction stimulates de novo lipogenesis in hepatocytes while simultaneously impairing muscle glucose uptake, creating a pathological metabolic state that propagates systemic insulin resistance (157)

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Ladhani et al., 2010

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From the Unpublished Journals of Fred Whiteside edited by Dorothy M

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