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Description

Archived from the original on 21 March 2025

Cellular Research Pentadecapeptide derived from a protective sequence in human gastric juice

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In 1970, James Bartley and Roger Chalkley showed that histones of calf thymus nucleohistone are protease resistant when complexed with DNA, whereas when freed from DNA, they rapidly degraded, indicating the presence of DNA-binding-induced structure (Doolittle, 1973)