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doi: 10.1007/s00203-025-04280-9 18 Kraut-CohenJ.ShapiroO

Reductive carboxylation A process that occurs in some normal and cancer cells whereby -ketoglutarate proceeds 'backwards' through the tricarboxylic acid cycle, being reduced through the consumption of NADPH by isocitrate dehydrogenase in the non-canonical reverse reaction to form citrate

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Side effects followed the pattern typical of incretin-based therapies

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Evidence shows that BaP could activate interleukin 6 (IL6) production and suppress nitric oxide-induced apoptosis in VSMCs