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Variants located in seven extracellular matrix genes were associated with advanced AMD and not early/intermediate AMD, suggesting that extracellular remodeling pathway(s) become relevant in advanced disease 72

Key Laboratory for Animal Disease-resistance Nutrition of China Ministry of Education, Sichuan Agricultural University, Chengdu 611130, China

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An IKK-independent phosphorylation of the IkB complex has also been reported, which leads to a similar outcome, i.e

Typical drug development paradigms that target single proteins insufficiently address this challenge [14,15,16,17]