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J Clini Sleep Med

Reconstitute: Add 1.0 mL bacteriostatic water ~ 10.0 mg/mL concentration

Current FDA labeling for semaglutide products includes warnings or precautions involving: Acute pancreatitis Acute gallbladder disease Acute kidney injury due to volume depletion Severe gastrointestinal reactions Hypoglycemia when combined with insulin or insulin secretagogues Diabetic retinopathy complications in susceptible patients Serious hypersensitivity reactions Pulmonary aspiration risk during general anesthesia or deep sedation Semaglutide labeling also contains a boxed warning regarding thyroid C-cell tumors observed in rodents

Other considerations: Not for anemia of other causes (oxygenation or B12 deficiency, etc.)

Headache: Occasional, possibly from metabolic shifts

medication interactions are manageable with attention and data