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It is characterized by abnormal metabolism of the three major nutrients and suppression of mitochondrial oxidative phosphorylation (OXPHOS), which contributes to the onset and development of DKD

122,123 Magnesium deficiency has the potential to induce neuronal excitability and augment neuromuscular transmission

Balvers RK, et al

Hence, all these lines impaired in glutathione biosynthesis indicate its important role in AITC-induced physiological responses

However, some pregnant women with HELLP (hemolysis, elevated liver enzymes, or low platelet counts) syndrome (10%15%) or eclampsia (38%) may not exhibit hypertension or proteinuria, which are associated with higher rates of maternal and fetal morbidities than in mild preeclampsia (432, 433)

GCL is composed of a catalytic (GCLC, Mr ~73 kDa) and a modifier (GCLM, Mr ~31 kDa) subunit [32] (summarized in Fig