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Treatment with artemisinin, an anti-malarial drug with immune-regulatory and anti-tumor effects, synergizes with anti-PD-L1 therapy in melanoma tumor models, inhibiting MDSC immunosuppression and accumulation and promoting T cell anti-tumor effects (162)

Some can be run concurrently and some cannot

Microglial pro-inflammatory polarization is further sustained by altered potassium (KCNJ2, potassium inwardly rectifying channel subfamily J member 2) and calcium (TRPM2, transient receptor potential melastatin 2) channel activity, which regulate cytokine release and immune activation

Perfetti R, Zhou J, Doyle ME, and Egan JM

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Medication Considerations: Why Your Vet Should Be Involved Medication interactions are one of the most overlooked reasons to involve a veterinarian