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Vicious cycle of iron dyshomeostasis and A/tau An abnormal increase in iron levels in the AD brain is a well-documented phenomenon, especially in the regions most severely affected by neurodegeneration (6)

[DOI] [PubMed] [Google Scholar] 32.Kumar C., Igbaria A., DAutreaux B., Planson A.G., Junot C., Godat E., Bachhawat A.K., Delaunay-Moisan A., Toledano M.B

Diet is an important factor affecting the incidence rate

The availability of PHGDH inhibitors presents an exciting opportunity for preclinical and clinical trials targeting patients with PHGDH-amplified tumors [38]

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J Neurol Neurosurg Psychiatry 75 : 689695