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2014 , 114 , e39-45

AsA and GSH, as powerful antioxidants of plant cells, can detoxify H 2 O 2 to H 2 O, and the metabolic pools of AsA and GSH are tightly linked by the activity of the enzymes involved in the AsAGSH cycle, i.e., ascorbate peroxidase (APX), glutathione peroxidase (GPX), monodehydroascorbate reductase (MDHAR), dehydroascorbate reductase (DHAR), and glutathione reductase (GR) (Mishra et al., 2022)

A unique delivery platform involves the use of pHLIP (pH [low] insertion peptide) conjugates for the targeted administration of antimiRs, including antimiR-155

Metformin therapy has been observed to reduce the risk of dementia in diabetes (Wang et al., 2021)

As an important part of metabolic reprogramming in the tumors, reprogramming of glutamine metabolism is considered to have pleiotropic effects on cellular functions, such as macromolecule synthesis, energy generation, mTOR activation, maintenance of reactive oxygen species (ROS) balance and anti-tumor acidic microenvironment

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