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Increased apoptotic sensitivity of glioblastoma enables therapeutic targeting by BH3-mimetics

In neuronal preparations, GCPRs activated by caffeine, glutamate via mGluR, GABA via GABA B receptors, or calcitonin-gene-related protein (CGRP) receptor via CGRP have been shown to induce release of BDNF (Balkowiec and Katz 2002

2015 Jan 21:2015:0611 (Ver) Helen Marx, Pina Amin, John H Lazarus

In order to assess the alteration of intracellular ferritin levels upon SA treatment both the cell lines with their respective controls were used to perform ferrozine assay