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Except as provided in paragraphs (b)(1)(ii)(B) through (F) of this section, benchmarks will be based on performance by collection type, from all available sources, including MIPS eligible clinicians and APMs, to the extent feasible, during the applicable baseline or performance period

In the CY 2021 PFS rulemaking (85 FR 50210 through 50211

Masnec, S., Kokot, A., Zlatar, M., Kalauz, M., Radi, B., Klicek, R., Drmic, D., Lazi, R., Seiwerth, S., & Sikiric, P

However, the reality is more complex

others dont (see the page on tolerance)

In the functional medicine world, it is considered one of the most common unknown disorders