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Primary biliary cholangitis classically presents with severe fatigue, pruritus, hepatomegaly, and elevated alkaline phosphatase due to progressive destruction of intrahepatic bile ducts

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As rotenone and antimycin A block electron flow through the ETC, mitochondrial membrane potential drops as indicated by decreased TMRM signal which would limit NADPH regeneration and downstream antioxidant responses

Proteomic analysis of aqueous humor from primary open angle glaucoma patients on drug treatment revealed altered complement activation cascade

Autophagy was enhanced in MPP+-treated SH-SY5Y cells upon treatment with coated nanoparticles, as confirmed by monodansylcadaverine (MDC) staining

Roughly 30% of people with major depressive disorder (MDD) experience treatment-resistant depression (TRD)